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Comparison of the resting (0 prepulses) and use-dependent (after 100 prepulses) modification of five rat sodium channel isoforms expressed in Xenopus oocytes. Data for rat Nav1.7 channels are taken from the data set shown in Fig 5. Data for rat Nav1.2, rat Nav1.3, Nav1.6 and Nav1.8 channels are from previous studies in this laboratory [11,15,16]. Asterisks indicate significant use-dependent enhancement of channel modification (paired t-tests, P < 0.05).
