Table 2.
Treatment group | n | Birth weight (g) | Anogenital distance (mm) [distance normalized for body weight] | |
---|---|---|---|---|
Male pups | ||||
Control | 45 | 6.1 ± 0.7 | 3.68 ± 0.30 | [0.61 ± 0.08] |
S-(−)equol | 40 | 6.6 ± 1.0a,b | 3.87 ± 0.37c | [0.59 ± 0.06] |
R-(+)equol | 52 | 6.0 ± 0.7 | 3.75 ± 0.33 | [0.63 ± 0.10] |
Female pups | ||||
Control | 47 | 5.8 ± 0.9 | 1.67 ± 0.26 | [0.29 ± 0.05] |
S-(−)equol | 44 | 6.3 ± 0.8a,b | 1.81 ± 0.25c | [0.29 ± 0.04] |
R-(+)equol | 53 | 5.8 ± 0.6 | 1.74 ± 0.21 | [0.30 ± 0.05] |
p ≤ 0.008 S-(−)equol-treated pups were heavier than control pups.
p ≤ 0.002 S-(−)equol-treated pups were heavier than R-(+)equol-treated pups.
p ≤ 0.011 S-(−)equol-treated pups had longer anogenital distances than control pups, this significance was lost when normalized for body weight.