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. Author manuscript; available in PMC: 2012 Aug 25.
Published in final edited form as: J Med Chem. 2011 Jul 20;54(16):5858–5867. doi: 10.1021/jm200591t

Scheme 1.

Scheme 1

Synthesis of Fluorescent Compound 1 Analogues: fluorescent tag at the piperazine.a

aReagents: (a) 6-Br(CH2)5CN; (b) LiAlH4; (c) CH3COCl; (d) HCl; (e) ZnCl2, NaCNBH3; (f) Dansyl chloride; (g) NBD-chloride.