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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Immunol. 2011 May 2;186(11):6136–6147. doi: 10.4049/jimmunol.1001931

Figure 6. B cells from BCMA−/− lpr mice have normal BCR- and BAFF-mediated NF-κB activation.

Figure 6

(A) BCMA mRNA expression levels relative to HPRT in purified splenic B cells and representative FACS plots of BCMA protein expression by B cells and PCs in the spleens of 4-mo-old mice are shown. NS, not significant. n = 5–6 mice. (B) Immunoblot analysis of cytoplasmic extracts prepared from 24 hr stimulated cells was performed using antibodies against p100, p52, and β-actin. Nuclear extracts were probed with antibodies recognizing p52, p65, and HDAC1. Data shown are representative of three individual experiments.