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. Author manuscript; available in PMC: 2011 Sep 27.
Published in final edited form as: Mutat Res. 2007 Aug 7;637(1-2):161–172. doi: 10.1016/j.mrfmmm.2007.08.001

Figure 2.

Figure 2

Isolated DNA–peptide crosslinks. DNA– peptide crosslinks were obtained using either γ-HOPdG-adducted 12-mer (A), or γ-HOPdG-adducted 30-mer (B), or γ-HOPdA-adducted 12-mer (C). Following to purification, DNA–peptide crosslinks were tested for purity by PAGE under denaturing conditions (in the presence of 8 M urea). DNAs shown are: (M) oligodeoxynucleotide sizing markers, (1) oligodeoxynucleotides adducted with either γ-HOPdG or γ-HOPdA, and (2) corresponding oligodeoxynucleotides modified with the reduced KWKK crosslink.