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. Author manuscript; available in PMC: 2011 Sep 27.
Published in final edited form as: Mucosal Immunol. 2008 May 14;1(4):309–316. doi: 10.1038/mi.2008.18

Table 2.

Cytokine levels in cervicovaginal lavage samples from HIV-1-uninfected and HIV-1-infected CSWs, and HIV-1-uninfected non-CSW control subjects

HIV-1-uninfected CSWs HIV-1-infected CSWs HIV-1-uninfected non-CSW controls P-valuea
N=57 N=52 N=73
IL-2 0.2 (1.4) 0.7 (2.6) 0.3 (1.4) NS
IL-4 0 0 0 NS
IL-6 135.2 (571.0) 83.8 (148.6) 151.8 (371.4) NS
IL-10 1.31 (3.6) 3.0 (1.8) 7.5 (36.4) NS
TNF-α 6.31 (14.0) 17.7 (39.3)b 9.6 (23.4) 0.015
IFN-γ 3.95 (14.2) 24.0 (106.3)c 7.7 (26.2) 0.008

CSW, commercial sex worker; HIV-1, human immunodeficiency virus type 1; IFN, interferon; IL, interleukin; N, number of participants; NS, nonsignificant; TNF, tumor necrosis factor.

Data are mean (s.d.) pg ml−1.

The lower detection limit for each assay was 2.6 pg ml−1 for IL-2 and IL-4, 3.0 pg ml−1 for IL-6, 2.8 pg ml−1 for IL-10 and TNF-α, and 7.1 pg ml−1 for IFN-γ.

a

P-values for the comparison across all groups were calculated with one-way analysis of variance test.

b

P=0.006 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected CSWs, and P=0.02 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected non-CSWs as determined by Mann–Whitney U-test.

c

P=0.031 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected CSWs, and P=0.006 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected non-CSWs as determined by Mann–Whitney U-test.