Table 2.
HIV-1-uninfected CSWs | HIV-1-infected CSWs | HIV-1-uninfected non-CSW controls | P-valuea | |
---|---|---|---|---|
N=57 | N=52 | N=73 | ||
IL-2 | 0.2 (1.4) | 0.7 (2.6) | 0.3 (1.4) | NS |
IL-4 | 0 | 0 | 0 | NS |
IL-6 | 135.2 (571.0) | 83.8 (148.6) | 151.8 (371.4) | NS |
IL-10 | 1.31 (3.6) | 3.0 (1.8) | 7.5 (36.4) | NS |
TNF-α | 6.31 (14.0) | 17.7 (39.3)b | 9.6 (23.4) | 0.015 |
IFN-γ | 3.95 (14.2) | 24.0 (106.3)c | 7.7 (26.2) | 0.008 |
CSW, commercial sex worker; HIV-1, human immunodeficiency virus type 1; IFN, interferon; IL, interleukin; N, number of participants; NS, nonsignificant; TNF, tumor necrosis factor.
Data are mean (s.d.) pg ml−1.
The lower detection limit for each assay was 2.6 pg ml−1 for IL-2 and IL-4, 3.0 pg ml−1 for IL-6, 2.8 pg ml−1 for IL-10 and TNF-α, and 7.1 pg ml−1 for IFN-γ.
P-values for the comparison across all groups were calculated with one-way analysis of variance test.
P=0.006 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected CSWs, and P=0.02 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected non-CSWs as determined by Mann–Whitney U-test.
P=0.031 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected CSWs, and P=0.006 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected non-CSWs as determined by Mann–Whitney U-test.