Table 4. Selected pair-wise comparisons of individual drugs.

Drug Tested	Reference Drug in the Comparison
	Rofecoxib	Diclofenac	Ibuprofen	Naproxen	Celecoxib
Etoricoxib	1.29 (0.86, 1.93), n = 3 studies	1.36 (0.89, 2.09), n = 3 studies	1.68 (1.14, 2.49), n = 3 studies	1.75 (1.16, 2.64), n = 3 studies
Etodolac		0.95 (0.78, 1.16), n = 5 studies	1.04 (0.88, 1.24), n = 7 studies	1.10 (0.96, 1.26), n = 7 studies
Diclofenac	1.0 (0.89, 1.12), n = 18 studies		1.13 (1.03, 1.24), n = 27 studies	1.22 (1.11, 1.35), n = 25 studies	1.15 (1.02, 1.30), n = 19 studies
Naproxen			0.92 (0.87, 0.99), n = 32 studies	__	0.96 (0.81, 1.13), n = 23 studies
Meloxicam				1.11 (1.0, 1.23), n = 6 studies
Indomethacin				1.23 (1.10, 1.39), n = 15 studies

Values are pooled RRRs and 99% CIs. Bold indicates significant difference at p<0.0033 (the Bonferroni-adjusted threshold p-value; n = 15 comparisons; alpha = 0.05).