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. 2011 Sep 27;6(9):e25400. doi: 10.1371/journal.pone.0025400

Table 2. Comparison of fold change values of 20 genes (with P≤0.05) selected from the mRNA-seq platform to qRT-PCR and cDNA microarray.

Gene symbol Gene Name mRNA-seq data (P≤0.05) qRT-PCR (Fold change) cDNA microarray (Fold change)
Affecteda Unaffecteda Fold change
AFAP1 Actin filament associated protein 1 75.1 37.5 2.00 1.97 1.94
CCRL1 b Chemokine (C-C motif) receptor-like 1 0.19 22.8 −119.3 −98.3 −1.87
CHPF Chondroitin polymerizing factor 142.3 231.9 −1.63 −1.80 −1.59
CRIP1 Cysteine-rich intestinal protein 1 39.0 95.0 −2.44 −6.32 −1.81
DKK2 Dickkopf homolog 2 0.16 2.81 −18.1 −17.3 −2.30
DYNC1I1 Dynein, cytoplasmic 1, intermediate chain 1 0.02 0.56 −30.8 −35.9 −1.08c
EMP1 Epithelial membrane protein 1 99.4 217.2 −2.18 −2.06 −2.72
EXT1 Exostosin 1 184.3 104.3 1.77 1.95 1.55
FAM20A Family with sequence similarity 20, member A 0.27 7.48 −27.7 −32.2 −2.04
FBLN5 Fibulin-5 73.1 172.8 −2.36 −2.60 −2.03
GPR160 G protein-coupled receptor 160 0.78 0.02 41.8 1.37 1.08c
HTR1B b 5-hydroxytryptamine (serotonin) receptor 1B 0.87 0.01 62.0 4.15 1.51
KIF23 Kinesin family member 23 601.9 2.03 295.9 1.17 1.30c
LRRK2 Leucine-rich repeat kinase 2 0.05 1.30 −27.1 −29.8 n/a
LXN Latexin 10.7 0.10 111.4 166.3 2.22
MEST Mesoderm-specific transcript homolog 83.6 4.56 18.3 36.7 1.80
RAP1B b Ras-related protein 1b 78.9 39.1 2.02 1.46 −1.21c
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 19.1 0.47 40.3 35.7 17.3
SOD3 b Superoxide dismutase 3, extracellular 6.44 81.1 −12.6 −25.1 −1.44
STC2 Stanniocalcin 2 149.3 85.9 1.74 1.90 1.52c
a

values based on RPKM normalization;

b

one qRT-PCR probe used;

c

not significant.