Table 4. Top 20 overrepresented Gene Ontology (GO) terms using GOStat in the mRNA-seq data set (based on disease status, P≤0.05 and ≥±2.0 fold change, 708 genes).
GO ID | GO category | P-value | # Genes/ GO ID |
278 | mitotic cell cycle | 3.98×10−53 | 44 |
279 | M phase | 5.26×10−52 | 42 |
22403 | cell cycle phase | 6.64×10−48 | 45 |
22402 | cell cycle process | 1.37×10−42 | 58 |
7049 | cell cycle | 4.51×10−41 | 68 |
48856 | anatomical structure development | 2.50×10−30 | 105 |
8283 | cell proliferation | 1.05×10−29 | 56 |
7275 | multicellular organismal development | 5.74×10−29 | 113 |
32502 | developmental process | 5.74×10−29 | 145 |
32501 | multicellular organismal process | 5.72×10−28 | 157 |
48731 | multicellular systemic organismal development | 9.09×10−26 | 86 |
48513 | organ development | 1.38×10−24 | 68 |
87 | M phase of mitotic cell cycle | 2.21×10−24 | 40 |
7067 | mitosis | 8.97×10−24 | 39 |
51301 | cell division | 2.17×10−23 | 39 |
65007 | biological regulation | 2.27×10−18 | 211 |
50789 | regulation of biological process | 1.37×10−14 | 188 |
74 | regulation of progression through cell cycle | 3.22×10−14 | 27 |
48869 | cellular developmental process | 6.84×10−14 | 77 |
30154 | cell differentiation | 6.84×10−14 | 77 |