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. 2011 Sep 27;6(9):e25400. doi: 10.1371/journal.pone.0025400

Table 4. Top 20 overrepresented Gene Ontology (GO) terms using GOStat in the mRNA-seq data set (based on disease status, P≤0.05 and ≥±2.0 fold change, 708 genes).

GO ID GO category P-value # Genes/ GO ID
278 mitotic cell cycle 3.98×10−53 44
279 M phase 5.26×10−52 42
22403 cell cycle phase 6.64×10−48 45
22402 cell cycle process 1.37×10−42 58
7049 cell cycle 4.51×10−41 68
48856 anatomical structure development 2.50×10−30 105
8283 cell proliferation 1.05×10−29 56
7275 multicellular organismal development 5.74×10−29 113
32502 developmental process 5.74×10−29 145
32501 multicellular organismal process 5.72×10−28 157
48731 multicellular systemic organismal development 9.09×10−26 86
48513 organ development 1.38×10−24 68
87 M phase of mitotic cell cycle 2.21×10−24 40
7067 mitosis 8.97×10−24 39
51301 cell division 2.17×10−23 39
65007 biological regulation 2.27×10−18 211
50789 regulation of biological process 1.37×10−14 188
74 regulation of progression through cell cycle 3.22×10−14 27
48869 cellular developmental process 6.84×10−14 77
30154 cell differentiation 6.84×10−14 77