Table 5. Top 20 overrepresented KEGG pathways in the cDNA microarray data set (based on disease status, P≤0.05 and ≥±2.0 fold change, 206 genes).
| Pathway name | # input genes in pathway | % input genes in pathway | P-value |
| Jak-STAT signaling pathwaya | 9 | 4.39 | 4.46×10−5 |
| Cell adhesion molecules (CAMs)a | 8 | 3.902 | 1.10×10−4 |
| Wnt signaling pathway | 8 | 3.902 | 3.71×10−4 |
| Focal adhesiona | 7 | 3.415 | 7.77×10−3 |
| Melanomaa | 4 | 1.951 | 8.89×10−3 |
| Regulation of actin cytoskeletona | 7 | 3.415 | 0.0101 |
| Hematopoietic cell lineage | 4 | 1.951 | 0.0147 |
| Colorectal cancer | 4 | 1.951 | 0.0166 |
| TGF-beta signaling pathwaya | 4 | 1.951 | 0.0180 |
| Prostate cancer | 4 | 1.951 | 0.0210 |
| Cytokine-cytokine receptor interaction | 7 | 3.415 | 0.0238 |
| Vibrio cholerae infection | 3 | 1.463 | 0.0270 |
| Acute myeloid leukemia | 3 | 1.463 | 0.0296 |
| Pathways in cancera | 8 | 3.902 | 0.0355 |
| Systemic lupus erythematosus | 4 | 1.951 | 0.0422 |
| p53 signaling pathwaya | 3 | 1.463 | 0.0445 |
| Thyroid cancer | 2 | 0.976 | 0.0455 |
| Complement and coagulation cascadesa | 3 | 1.463 | 0.0461 |
| Antigen processing and presentation | 3 | 1.463 | 0.0478 |
a
pathways found in both platforms.