Table 6. Top 20 overrepresented KEGG pathways from the mRNA-seq data set (based on disease status, P≤0.05 and ≥±2.0 fold change, 708 genes).

Pathway Name	# input genes in pathway	% input genes in pathway	P-value
Cell cycle	18	2.542	2.68×10−8
Jak-STAT signaling pathwaya	12	1.695	5.37×10−3
Pathways in cancera	20	2.825	6.06×10−3
p53 signaling pathwaya	7	0.989	6.99×10−3
Cell adhesion molecules (CAMs)a	10	1.412	0.0122
Renin-angiotensin systema	3	0.424	0.0172
TGF-beta signaling pathwaya	7	0.989	0.0234
Regulation of actin cytoskeletona	13	1.836	0.0240
Complement and coagulation cascadesa	6	0.847	0.0261
Primary immunodeficiency	4	0.565	0.0273
Melanomaa	6	0.847	0.0295
Pancreatic cancer	6	0.847	0.0313
Focal adhesiona	12	1.695	0.0328
Gap junction	7	0.989	0.0376

^apathways found in both platforms.