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. 2011 Sep 27;6(9):e25610. doi: 10.1371/journal.pone.0025610

Figure 2. Antigen-specific ex vivo IFN-γ responses.

Figure 2

(a) in response to a wild-type Streptococcus pneumoniae strain (WT), (b) an isogenic pneumolysin (Ply)–deficient mutant (Ply-), (c) M. tuberculosis PPD and (d) influenza for 16 hours by IFN-γ enzyme-linked immunosorbent spot (ELISPOT) stimulation. Collated data from controls (n = 12–15) and those infected with HIV (≥500 (n = 7–10) 350-500 (n = 9–11), ≤350 (n = 14–17) CD4 T cells/µl). Black horizontal bars represent median values of total antigen specific responses above background. Statistical significance was analyzed by the Mann Whitney U test.