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. 2011 Oct;179(4):1638–1644. doi: 10.1016/j.ajpath.2011.06.020

Figure 4.

Figure 4

Survival by EGFR IHC in grade II oligodendrogliomas. A: Grade II oligodendrogliomas show progressively worse survival with increasing EGFR IHC intensity. P = 0.02. See Table 3 for specific intergroup P values. B: Adjusting for 1p/19q codeletion required combining cases that were EGFR IHC negative (neg), weak, and moderate (mod) into one group (neg-mod), with strong EGFR cases as a separate category, then segregating according to 1p/19q status. Even cases with 1p/19q codeletion showed worse survival if EGFR expression was strong. P = 0.02 overall, *P = 0.05, and **P = 0.004. C: There was no difference in the likelihood of 1p/19q codeletion between oligodendrogliomas that were strong for EGFR versus those with weaker staining. P = 0.25.