Table 2.
Genes Showing the Greatest Increase in Expression in KDFs Compared to NDFs in Microarray Analysis
| Gene name | Gene symbol | Fold change | UniGene ID |
|---|---|---|---|
| MRNA; cDNA DKFZp686A0837 (from clone DKFZp686A0837) | — | 78.793242 | Hs.638566 |
| Cartilage oligomeric matrix protein | COMP | 48.50293 | Hs.1584 |
| Secreted frizzled-related protein 2 | SFRP2 | 42.224253 | Hs.481022 |
| v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | KIT | 39.396621 | Hs.479754 |
| C-type lectin domain family 12, member A | CLEC12A | 36.758347 | Hs.190519 |
| Fibroblast growth factor receptor 2 | FGFR2 | 34.296751 | Hs.533683 |
| Testis expressed 9 | TEX9 | 25.992077 | Hs.511476 |
| Retinoic acid receptor responder (tazarotene induced) 2 | RARRES2 | 25.992077 | Hs.647064 |
| Transmembrane protein 16A | TMEM16A | 22.627417 | Hs.503074 |
| Transcribed locus | — | 19.698311 | Hs.662908 |
| Armadillo repeat containing, X-linked 4 | ARMCX4 | 18.379174 | Hs.399873 |
| Death-associated protein kinase 1 | DAPK1 | 17.148375 | Hs.380277 |
| cDNA FLJ38181 fis, clone FCBBF1000125 | — | 16 | Hs.143134 |
| cDNA clone IMAGE:4830514 | — | 16 | Hs.570820 |
| Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | CSF2RB | 16 | Hs.592192 |
| Chondrolectin | CHODL | 14.928528 | Hs.283725 |
| Dermatopontin | DPT | 14.928528 | Hs.80552 |
| Insulin-like growth factor 2 (somatomedin A) /// insulin- insulin-like growth factor 2 | IGF2 /// INS-IGF2 | 13.928809 | Hs.523414 |
| Gap junction protein, alpha 5, 40kDa | GJA5 | 12.996038 | Hs.447968 |
| Inter-alpha (globulin) inhibitor H5 | ITIH5 | 12.996038 | Hs.498586 |
| cDNA FLJ30757 fis, clone FEBRA2000468 | — | 12.996038 | Hs.662237 |
| G protein–coupled receptor 37 (endothelin receptor type B-like) | GPR37 | 12.125733 | Hs.406094 |
| Unc-5 homolog B (C. elegans) | UNC5B | 12.125733 | Hs.585457 |
| Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | NFKBIL1 | 11.313708 | Hs.2764 |
| Hypothetical gene supported by BC008048 | LOC440934 | 10.556063 | Hs.238964 |
| Dopamine receptor D1 | DRD1 | 10.556063 | Hs.2624 |
| Signal-induced proliferation-associated 1 like 2 | SIPA1L2 | 10.556063 | Hs.268774 |
| Deleted in bladder cancer 1 | DBC1 | 10.556063 | Hs.532316 |
| Calcium/calmodulin-dependent protein kinase ID /// Hypothetical protein LOC283070 | CAMK1D /// LOC283070 | 10.556063 | Hs.600547 |
| Carboxypeptidase Z | CPZ | 10.556063 | Hs.78068 |
NDFs, normal skin-derived fibroblasts.