Table 3.
Comparison of Gene Expression Patterns between KDFs and NDFs from the Same Patient in the Microarray Analysis
| Up-regulated | Down-regulated | |
|---|---|---|
| Extracellular matrix constituents | 11 | 8 |
| Growth factors and their receptors | 18 | 17 |
| Transcription factors and proteins binding with DNA | 25 | 72 |
| Apoptosis | 15 | 0 |
| Matrix metallopeptidase | 3 | 12 |
| Cellular skeleton and movement | 3 | 9 |
| Cytokines and their binding proteins | 5 | 24 |
| Cell metabolism | 1 | 0 |
| Unknown function | 106 | 202 |
| Others | 187 | 414 |
| TOTAL | 374 | 758 |
KDFs, keloid-derived fibroblasts; NDFs, normal skin-derived fibroblasts.