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. 2011 Oct;179(4):1988–2000. doi: 10.1016/j.ajpath.2011.06.044

Table 2.

KEGG Pathways That Are Specific for the WTA-WTD or D7E-WTA Studies

KEGG ID KEGG pathway P value No. of genes/pathway Deregulated genes
No. %
D7E deregulated
 3050 Proteasome 8.54E-05 45 10 22.2
 4120 Ubiquitin-mediated proteolysis 2.45E-02 131 15 11.5
 4530 Tight junction 8.17E-03 121 17 14.0
 4520 Adherens junction 4.19E-02 73 10 13.7
 4510 Focal adhesion 4.21E-02 186 21 11.3
 4810 Regulation of actin cytoskeleton 2.94E-02 199 24 12.1
 4910 Insulin signaling pathway 1.04E-02 132 16 12.1
 4912 GnRH signaling pathway 1.23E-02 96 12 12.5
WTA deregulated
 4110 Cell cycle 9.47E-03 111 15 13.5
 4310 Wnt signaling pathway 1.11E-02 143 17 11.9

For each KEGG pathway P value, the number of deregulated genes and the corresponding percentage from the total annotated genes are indicated.