Table 4.
Correlation between Expression of MEG3 and Other Maternally Expressed Genes in the DLK1-MEG3 Locus in Normal Pituitary and in Pituitary Adenomas
| Gene symbol⁎ | Pearson's r | P value |
|---|---|---|
| MEG8 | 0.863 | <0.001 |
| SNORD113-5 | 0.642 | <0.001 |
| MIR369-5p | 0.533 | <0.001 |
| MIR376c | 0.522 | <0.001 |
| MIR323-3p | 0.463 | <0.001 |
| MIR329 | 0.463 | <0.001 |
| MIR154 | 0.453 | <0.001 |
| MIR369-3p | 0.439 | <0.001 |
| MIR377 | 0.436 | 0.001 |
| MIR433 | 0.424 | 0.001 |
| MIR136 | 0.410 | 0.002 |
| MIR370 | 0.378 | 0.005 |
| MIR432 | 0.377 | 0.005 |
| MIR410 | 0.332 | 0.014 |
| MIR299-5p | 0.28 | 0.040 |
| MIR134 | 0.259 | 0.058 |
| MIR127-3p | 0.175 | 0.206 |
| MIR337 | 0.053 | 0.701 |
| MIR431 | −0.050 | 0.722 |
| MIR380 | −0.113 | 0.418 |
| MIR770-5p | −0.189 | 0.170 |
Associations between MEG3 expression levels and the rest of the maternally expressed genes were examined by Pearson's correlation coefficient. A P value of <0.05 was interpreted as significant. (n = 54).
⁎
For miRNA genes, -3p and -5p denote miRNAs derived from the 3′ arm and the 5′ arm of the precursor miRNA, respectively.