Table 3.
Genes that Comprise the Extracellular Matrix, Axonogenesis, Defense Response, and Angiogenesis Gene Sets Identified by DAVID Analysis of Human Th2-High Asthma and the Rhesus Asthma Model
| DAVID term (biology) | Agilent probe ID | Entrez gene ID | Gene symbol | Gene name |
|---|---|---|---|---|
| Extracellular matrix | A_23_P211212 | 80781 | COL18A1 | Collagen, type XVIII, alpha 1 |
| A_23_P42322 | 1302 | COL11A2 | Collagen, type XI, alpha 2 | |
| A_24_P334130 | 2335 | FN1 | Fibronectin 1 | |
| A_23_P44291 | 100134403 | CRTAP | Cartilage associated protein | |
| A_24_P179225 | 4147 | MATN2 | Matrilin 2 | |
| A_23_P24870 | 960 | CD44 | CD44 molecule (Indian blood group) | |
| A_23_P112554 | 1306 | COL15A1 | Collagen, type XV, alpha 1 | |
| A_23_P7642 | 6678 | SPARC | Secreted protein, acidic, cysteine-rich (osteonectin) | |
| A_24_P315821 | 339366 | ADAMTSL5 | ADAMTS-like 5 | |
| A_23_P124084 | 4016 | LOXL1 | Lysyl oxidase-like 1 | |
| A_23_P7727 | 1404 | HAPLN1 | Hyaluronan and proteoglycan link protein 1 | |
| A_23_P159325 | 51129 | ANGPTL4 | Angiopoietin-like 4 | |
| A_23_P59388 | 667 | DST | Dystonin | |
| A_23_P204286 | 4256 | MGP | Matrix Gla protein | |
| A_23_P20697 | 9719 | ADAMTSL2 | Similar to ADAMTS-like 2; ADAMTS-like 2 | |
| A_24_P331918 | 1291 | COL6A1 | Collagen, type VI, alpha 1 | |
| A_23_P68487 | 655 | BMP7 | Bone morphogenetic protein 7 | |
| A_32_P32254 | 1291 | COL6A1 | Collagen, type VI, alpha 1 | |
| A_23_P102117 | 80326 | WNT10A | Wingless-type MMTV integration site family, member 10A | |
| A_23_P56578 | 5212 | VIT | Vitrin | |
| A_23_P121533 | 10417 | SPON2 | Spondin 2, extracellular matrix protein | |
| Axonogenesis | A_23_P7752 | 57556 | SEMA6A | Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| A_32_P100974 | 6152 | RPL24 | Ribosomal protein L24; ribosomal protein L24 pseudogene 6 | |
| A_23_P65307 | 84189 | SLITRK6 | SLIT and NTRK-like family, member 6 | |
| A_24_P365807 | 1947 | EFNB1 | Ephrin-B1 | |
| A_23_P59388 | 667 | DST | Dystonin | |
| A_23_P55099 | 5578 | PRKCA | Protein kinase C, alpha | |
| A_32_P152586 | 7080 | NKX2-1 | NK2 homeobox 1 | |
| A_24_P519638 | 89884 | LHX4 | LIM homeobox 4 | |
| A_23_P210756 | 6616 | SNAP25 | Synaptosomal-associated protein, 25kDa | |
| A_23_P68487 | 655 | BMP7 | Bone morphogenetic protein 7 | |
| A_23_P132175 | 65078 | RTN4R | Reticulon 4 receptor | |
| A_24_P42624 | 8633 | UNC5C | Unc-5 homolog C (C. elegans) | |
| A_23_P121533 | 10417 | SPON2 | Spondin 2, extracellular matrix protein | |
| Defense response | A_23_P16384 | 199713 | NALP7 | NLR family, pyrin domain containing 7 |
| A_23_P502464 | 4843 | NOS2A | Nitric oxide synthase 2, inducible | |
| A_23_P26965 | 6357 | CCL13 | Chemokine (C-C motif) ligand 13 | |
| A_23_P215484 | 10344 | CCL26 | Chemokine (C-C motif) ligand 26 | |
| A_24_P334130 | 2335 | FN1 | Fibronectin 1 | |
| A_23_P24870 | 960 | CD44 | CD44 molecule (Indian blood group) | |
| A_23_P22660 | 10800 | CYSLTR1 | Cysteinyl leukotriene receptor 1 | |
| A_24_P12573 | 10344 | CCL26 | Chemokine (C-C motif) ligand 26 | |
| A_23_P25354 | 23676 | P2RX7 | Purinergic receptor P2X, ligand-gated ion channel, 7 | |
| A_23_P143331 | 650 | BMP2 | Bone morphogenetic protein 2 | |
| A_23_P209954 | 10578 | GNLY | Granulysin | |
| A_23_P119295 | 51295 | ECSIT | ECSIT homolog (Drosophila) | |
| Angiogenesis | A_23_P159325 | 51129 | ANGPTL4 | Angiopoietin-like 4 |
| A_24_P7950 | 10451 | VAV3 | Vav 3 guanine nucleotide exchange factor | |
| A_23_P48217 | 81575 | APOLD1 | Apolipoprotein L domain containing 1 | |
| A_24_P334130 | 2335 | FN1 | Fibronectin 1 | |
| A_32_P210642 | 51162 | EGFL7 | EGF-like-domain, multiple 7 | |
| A_23_P112554 | 1306 | COL15A1 | Collagen, type XV, alpha 1 |
DAVID, Database for Annotation, Visualization, and Integrated Discovery.