Figure 5.

Classification of gastric cancers based on protein expression patterns. A: Hierarchical clustering analysis of tumors based on CDK2 and AKT expression level revealed three large groups. All tumors in Group 1 (n = 21) had a low CDK2 and AKT expression. All tumors in Group 2 (n = 42) had a low expression of either CDK2 or AKT. Conversely, all tumors in Group 3 (n = 30) had a high CDK2 and AKT expression. Red indicates overexpression, green underexpression, black no change, and gray no expression. The columns represent samples and the rows represent proteins. B: Kaplan-Meier survival analysis showed that the overall survival of the patients with gastric cancer (n = 93) was worse in Groups 2 and 3, as compared with Group 1. P value was determined by log-rank test.