Figure 1.

Epidermal deletion of Jarid2 does not affect embryonic development of the epidermis. (A) Haematoxylin–eosin staining revealed no abnormalities in epidermal embryonic development of Jarid2 cKO mice. At least three control (K14Cre/Jarid2^wt/wt) and cKO mice were analysed for each time point shown. Scale bar: 100 μm. (B) Immunofluorescence of Ki67 and loricrin indicates that proliferation and differentiation are not modified during embryonic epidermal development upon Jarid2 deletion. Scale bar: 50 μm. (C) Higher magnification of skin sections shows a normal architecture for the embryonic hair follicles in absence of Jarid2. Scale bar: 50 μm.