Table 4.
Incidence rate, relative hazard (95% confidence intervals) and population attributable fractions for atrial fibrillation for risk factors in the Atherosclerosis Risk in Communities (ARIC) study, 1987 – 2007
No. at Risk |
No. Incident AF |
IR* | RH (95% CI) † | PAF % | 95% CI | |
---|---|---|---|---|---|---|
History of Cardiac Disease (%) |
||||||
Optimal | 13398 | 1259 | 5.00 | 0.54 (0.46-0.62) | 0.00 | - |
Elevated | 1200 | 261 | 12.17 | 1 [Ref] | 5.35 | 3.32 to 7.45 |
Blood pressure (%) | ||||||
Optimal | 5626 | 381 | 3.93 | 0.55 (0.48-0.63) | 0.00 | - |
Borderline | 3317 | 304 | 4.72 | 0.65 (0.56-0.74) | 2.89 | −0.11 to 5.64 |
Elevated | 5655 | 835 | 7.65 | 1 [Ref] | 21.6 | 16.8 to 26.7 |
BMI (%) | ||||||
Optimal | 4889 | 389 | 4.27 | 0.65 (0.56-0.74) | 0.00 | - |
Borderline | 5767 | 591 | 5.28 | 0.70 (0.62-0.79) | 5.16 | 0.93 to 9.26 |
Elevated | 3942 | 531 | 7.36 | 1 [Ref] | 12.7 | 9.30 to 16.3 |
Diabetes (%) | ||||||
Optimal | 7558 | 645 | 4.68 | 0.67 (0.58-0.78) | 0.00 | - |
Borderline | 5491 | 617 | 5.83 | 0.71 (0.61-0.82) | 0.78 | −3.52 to 4.84 |
Elevated | 1533 | 253 | 8.77 | 1 [Ref] | 3.08 | 0.91 to 5.30 |
Smoking (%) | ||||||
Optimal | 6077 | 510 | 4.23 | 0.55 (0.48-0.62) | 0.00 | - |
Borderline | 4769 | 550 | 5.76 | 0.60 (0.52-0.68) | 2.06 | −2.05 to 6.05 |
Elevated | 3752 | 460 | 7.45 | 1 [Ref] | 9.78 | 6.74 to 12.9 |
IR = Incidence Rate of AF per 1000 person-years adjusted for age (mean age = 54.2 years);
Adjusted for age, gender, race, study site, education, income and height and each of the other risk factors.