Table I. Genetic linkage in the National Institute of Mental Health (NIMH) pedigrees. Autosomal dominant model f(A)=0.0045. The HLOD is the LOD score under the assumption of genetic heterogeneity, ie, different genetic loci responsible for transmission of schizophrenia in different subgroups of families. The scores were computed using pairs of adjacent genetic markers. α is the estimate from the heterogeneity analysis of the proportion of linked pedigrees at any given locus.

Locus	HLOD score (α)
6q13-21	1.11 (0.35)
9q32	1.09 (0.40)
10p13	2.40 (0.45)
13q32	0.58 (0.25)
15q14	3.97 (0.95)
15q21	1.00 (0.50)
17p13	0.93 (0.40)
20q13	1.56 (0.45)