Table I. Abnormal involuntary movements assessed by the Abnormal Involuntary Movements Scale (AIMS) in patients with chronic schizophrenia, grouped according to magnesium superoxide dismutase (MnSOD) and dopamine D3, receptor (DRD3) genotype combinations. MnSOD-alalDRD3-ser. MnSOD ala9 allele carriers (ala-ala homozygotes and ala-val hétérozygotes), DRD3 ser9 homozygotes; MnSOD-alalDRD3-gly: MnSOD ala9 allele carriers, DRD3 gly9 carriers (ser-gly hétérozygotes and gly-gly homozygotes); MnSOD val/DRD3-ser: MnSOD val9 homozygotes, DRD3 ser9 homozygotes; MnSOD va/DRD3-gly: MnSOD val9 homozygotes, DRD3 gly9 carriers. By analysis of variance (ANOVA): F=6.16; df=3,102; P=0.0007 *P=0.0004 vs MnSOD-ala/DRD3-ser, P=0.046 vs MnSOD-ala/DRD3 gly (post-hoc Newman-Keuls test) SD, standard deviation.
| Genotype combination | N | AIMS total score | SD |
| MnSOD-ala/DRD3-ser | 29 | 2.6 | 2.7 |
| MnSOD-ala/DRD3-gly | 47 | 5.7 | 5.4 |
| MnSOD-val/DRD3-ser | 9 | 7.0 | 6.6 |
| MnSOD-val/DRD3-gly | 21 | 9.2 | 7.9* |