| 1. ANTIDEPRESSANT DRUGS |
| •Tricyclic and tetracyclic antidepressants (TCAs) |
| clomipramine (SRI>>NRI); amitriptyline (SRI>NRI) |
| imipramine, doxepine, amoxapine (NRI=SRI) |
| desipramine (NRI>SRI)) |
| maprotiline (NRI) |
| • Selective serotonin reuptake Inhibitors (SSRIs) |
| citalopram, escitalopram |
| fluoxetine (also NRI, and weak D7 receptor blocker) |
| fluvoxamine (also weak NRI, and melatonin agonist) |
| paroxetine (also NRI>>DaRI) |
| sertraline (also DaRI>>NRI) |
| • Selective serontonin and noradrenaline reuptake |
| inhibitors (SNRIs) |
| venlafaxine, milnacipran, duloxetine |
| • Noradrenaline α2 receptor antagonist and serotonin 5-HT2 |
| receptor antagonist |
| mianserine, mirtazapine |
| • Serotonin (5-HT2) receptor antagonists |
| trazodone, nefazodone |
| • Noradrenaline reuptake inhibitor |
| reboxetine |
| • Dopamine reuptake inhibitors |
| bupropion (also weak NI), methylphenydate |
| • Monoamine oxidase inhibitors(MAOIs) |
| irreversible and nonselective: iproniazide |
| reversible and selective: |
| MAOI-A (moclobemide, toloxatone) |
| MAOI-B (selegiline) |
| • Melatoninergic (MT1/2) receptor agonist and selective |
| 5-HT2 receptor antagonist |
| agomelatine |
| • Others |
| Tianeptine |
| herbal medicine: hypericum perforatum (St. John's wort) |
| amino acid derivative S-adenosylmethionine (SAM-e) |
| tryptophan and 5 hydroxytryptophan dietary supplements |
| 2. MOOD STABILIZERS |
| • Lithium salts |
| • Antiepileptics |
| carabazepine/oxcarbazepine, sodium valproate/divalproate/ |
| vaIpromide, la motrigine |
|
3. “NONCHEMICAL” THERAPIES
|
|
• Sleep deprivation (total: all night; partial: second half |
| of the night) |
| • Light therapy |
| • Electroconvulsive therapy |
| • Magnetic stimulation |
| • Vagus nerve stimulation |
| • Deep brain stimulation |
| 4. PSYCHOTHERAPY |
| • Cognitive therapy |
| • interpersonal psychotherapy |
| • Problem-solving therapy |
| • Psychodynamic-interpersonal psychotherapy |
| • Psychoanalytic oriented psychotherapy |
