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. 2006 Jun;8(2):241–258. doi: 10.31887/DCNS.2006.8.2/reitan

Table I. Drug coadministration with electroconvulsive therapy.

Drug Concomitant administration with ECT
Lithium13 Discontinue before ECT. Lithium decreases the intracellular production of
acetylcholine, may prolong the action of succinylcholine, and may prolong
seizure duration
Tricyclic antidepressant, monoamine oxidase inhibitors Safe
selective serotonin reuptake inhibitors14,15
Bupropion16 Controversial. Bupropion may cause prolonged seizure
Benzodiazepines Safe, but have an anticonvulsive activity, and might raise the seizure threshold
Antipsychotics17 Safe
Clozapine18 Controversial, might induce late seizures