Table 1.
Normo | Micro | Macro | P | |
---|---|---|---|---|
n | 34 | 21 | 13 | |
Age, years | 47±16 | 48±17 | 48±12 | 0.9 |
Male, % | 54 | 62 | 56 | |
Diabetes duration, years | 20±11 | 24±13 | 27±6 | 0.14 |
BMI | 28±5 | 27±4 | 28±7 | 0.72 |
Systolic blood pressure mm Hg | 129±20 | 135±16 | 140±19 | 0.17 |
Fasting glucose, mmol/1 | 10.0±4.4 | 9.5±2.7 | 9.4±3.8 | 0.89 |
HbA1c, % | 7.8±0.8 | 8.2±1.0 | 9.3±1.8« | 0.001 |
AER, μg/min | 6.1 ×/÷2.7 | 43.2×/÷1.6 | 827.8×/÷2.5 | |
iGFR, ml/min/1.73 m2 | 81±11 | 89±24 | 84±23 | 0.34 |
Total cholesterol, mmol/1 | 4.6±0.9 | 4.4±1.2 | 4.4±1.2 | 0.80 |
LDL-cholesterol, mmol/1 | 2.8±0.8 | 2.9±1.5 | 2.9±1.2 | 0.90 |
HDL-cholesterol, mmol/1 | 1.4±0.7 | 1.5±0.6 | 1.4±0.5 | 0.90 |
Triglycérides, mmol/1 | 0.8±0.4 | 1.2±0.8 | 1.4±0.8∗ | 0.01 |
Medication use, % | ||||
ACE inhibitors | 17 | 61 | 50 | 0.013 |
ARBs | 13 | 33 | 25 | 0.29 |
β-Blockers | 13 | 17 | 38 | 0.29 |
Diuretics | 13 | 6 | 38 | 0.09 |
Statins | 34 | 52 | 36 | 0.39 |
Data are means 8 SD except for AER, which is shown as the geometric mean ×/÷ tolerance factor and medication use, which is displayed as % use. ACE = Angiotensin-converting enzyme; ARB = angiotensin receptor blocker; HbA1c = glycated hemoglobin; iGFR = isotopic GFR.
p < 0.001 vs. Normo.