Table 1.
Retroviral Vectors for Targeted Infection
| Modification | Target Cell | References |
|---|---|---|
| EGF-MMP cleavable linker chimeric env | Cancer invasion, angiogenesis, inflammation | [16, 17, 20] |
| IL-2 chimeric env | IL-2 R | [27] |
| EGF chimeric env | EGFR | [15] |
| SCF-Factor Xa chimeric env | Stem cell (Kit) | [19] |
| vWF (collagen binding) chimeric env | Cancer (collagen expressing); vascular lesion | [23, 24] |
| Single-chain variable fragmented antibody (scFv) for EGFRvIII | Cancer (brain, breast, lung, ovary) | [29] |
| scFv for HMWMAA | Cancer | [22] |
| scFv from phage display | T cell | [28] |
| scFv for Carcino embryonic antigen (CEA) | Cancer | [30] |
| Receptor pseudotyping (CD4 and CXCR4) | HIV-1 infected cell | [31, 32] |