. Author manuscript; available in PMC: 2012 Oct 1.

Published in final edited form as: J Pharmacokinet Pharmacodyn. 2011 Aug 17;38(5):613–636. doi: 10.1007/s10928-011-9211-7

Table 1.

The estimates of model parameters.

Bayesian mixture

Conventional lognormal

Conventional normal

posterior mean (s.d.)

mean (s.e.)

49.1 (4.1)

32.5 (4.2)

29.0 (3.7)

100.3 (32.5)

190 (38.6)

199 (37.5)

Ω_{C l} (σ_{C l}^{2})

0.22 (0.06)

0.43 (0.16)

0.73 (0.17)

Ω_{V} (σ_{V}^{2})

0.29 (0.24)

0.62 (0.22)

0.87 (0.20)

σ²

0.10 (0.002)

0.63 (0.15)

0.35 (0.06)

w₁

0.69 (0.05)

–

w₂

0.29 (0.04)

–

w₃

0.02 (0.02)

–

1.07 (0.07)

–

0.25 (0.03)

–

5.82 (2.56)

–

3.31 (1.11)

–