Table 1. Inhibition of Cellular Proliferation.

Calculated concentrations of effective doses (ED) for sunitinib and pazopanib in inhibiting cellular proliferation against eight human renal cell carcinoma cell lines

Cell line	Compound (μM)	ED20	ED50	ED70	ED90
769-P	Sunitinib	6.3	15.1	24.6	45.6
	Pazopanib	6.8	60.3	>100	N/A
786-O	Sunitinib	3.6	20.7	45.2	90.5
	Pazopanib	7.9	>100	N/A	N/A
HRC-24	Sunitinib	13.1	17.1	20.4	30.0
	Pazopanib	11.2	>100	N/A	N/A
HRC-31	Sunitinib	9.7	12.8	15.3	21.5
	Pazopanib	4.8	32.4	>100	N/A
HRC-45	Sunitinib	7.9	12.1	15.8	24.8
	Pazopanib	9.1	36.7	79.8	>100
HRC-78	Sunitinib	5.2	6.9	8.4	13.4
	Pazopanib	10.3	44.0	>100	N/A
SK-45	Sunitinib	4.5	21.4	39.6	64.6
	Pazopanib	3.4	36.6	>100	N/A
SK-26b	Sunitinib	21.7	34.3	45.3	70.7
	Pazopanib	13.4	34.6	61.6	N/A