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. Author manuscript; available in PMC: 2012 Jun 4.
Published in final edited form as: Transl Stroke Res. 2011 Jun 4;2(3):411–423. doi: 10.1007/s12975-011-0087-z

Fig. 4.

Fig. 4

HDAC 3 is expressed in neuronal cell bodies, axons, in the nuclei, and distal processes of astrocytes. HDAC 3 exhibited a cytoplasmic (arrows) and axonal (arrowhead) pattern in cortical neurons (cortex) and co-localized with MAP2(+) neuronal cell bodies and axons (cortex, middle panel). HDAC 3 (right, upper panel) also co-localized with NF-200(+) axons (left, middle panel) in the corpus callosum. HDAC 3 was displayed in the nuclei (arrows) and proximal main processes (arrowheads) of GFAP(+) astrocytes in hippocampus (arrows) and SCWM (merged panels). Note the distinct punctate nature of HDAC 3 expression in both gray matter regions, co-localizing with distal processes of GFAP(+) astrocytes (stars). In the lower right panel, HDAC 3 labeling was absent in astrocyte end-feet (blue arrowhead), but outlined the vasculature (blue arrow)