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. 2011 Sep 28;6(9):e25243. doi: 10.1371/journal.pone.0025243

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Suzuki et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Hot spots of both secretion and binding of MMP-2 on the cell surface in a migrating cell. (B) Inactive pro-form of MMP-2 is frequently secreted on the leading edge and then bind to micro areas on the cell surface.