Table 2. Factors associated with death in a cohort of 762 successfully treated tuberculosis patients. Barcelona, 1995–2005.
Univariate Analysis | Multivariate Analysis | |||||
Variables | Hazard Ratio | 95%CI | p-value | Hazard Ratio | 95%CI | p-value |
Age (years) | ||||||
. Under 41 | 1 | - | - | 1 | - | - |
. 41 to 60 | 1.9 | 1.3–2.8 | 0.002 | 3.5 | 2.1–5.7 | <0.001 |
. Older than 60 | 5.3 | 3.8–7.5 | <0.001 | 14.6 | 8.9–24 | <0.001 |
Sex | ||||||
. Female | 1 | - | - | 1 | - | - |
. Male | 1.7 | 1.2–2.4 | 0.005 | 1.1 | 0.8–1.7 | 0.795 |
Country of origin | ||||||
. Foreign | 1 | - | - | 1 | - | - |
. Spain | 2.4 | 1.1–5.5 | 0.030 | 1.5 | 0.7–3.5 | 0.315 |
Residence in inner-city | ||||||
. No | 1 | - | - | 1 | - | - |
. Yes | 1.4 | 1–2 | 0.060 | 1.2 | 1.8–1.7 | 0.335 |
Alcohol abuse | ||||||
. No | 1 | - | - | 1 | - | - |
. Yes | 1.9 | 1.4–2.6 | <0.001 | 1.7 | 1.2–2.4 | 0.003 |
HIV-IDU * | ||||||
. HIV Neg- Non-IDU | 1 | - | - | 1 | - | - |
. HIV and IDU | 2.6 | 1.9–3.7 | <0.001 | 7.7 | 4.5–13.3 | <0.001 |
. HIV not IDU | 1 | 0.5–2 | 0.953 | 1.4 | 0.7–2.8 | 0.350 |
TB ** recurrence | ||||||
. No | 1 | - | - | 1 | - | - |
. Yes | 1.6 | 0.7–3.7 | 0.237 | 0.8 | 0.3–2 | 0.563 |
Chest- X-Ray | ||||||
.Abnormal non-cavitary | 1 | - | - | 1 | - | - |
. Cavitary | 1.6 | 1.1–2.4 | 0.028 | 1.3 | 0.8–2.2 | 0.235 |
. Normal | 0.6 | 0.4–0.9 | 0.008 | 0.7 | 0.5–1 | 0.068 |
. Unknown | 0.9 | 0.3–2.9 | 0.890 | 0.7 | 0.2–2.2 | 0.521 |
Previous TB treatment | ||||||
. Yes | 1 | - | - | 1 | - | - |
. No | 1.6 | 1.1–2.3 | 0.020 | 1.3 | 0.9–2.1 | 0.185 |
. Unknown | 2.2 | 1.2–4.2 | 0.015 | 1.1 | 0.6–2.4 | 0.719 |
*IDU: injecting drug users.
**TB: Tuberculosis.