Table 1. Demographic and clinical characteristics of the patients with hypersensitivity pneumonitis and idiopathic pulmonary fibrosis.
HP (n = 22) | IPF (n = 21) | Control (serum; n = 11) | Control (BAL; n = 4) | |
Age, yr | 52±12 | 66±8 | 42±20 | 53±15 |
Sex (M/F) | 4/18 | 14/7 | 2/9 | 3/1 |
Current or former smoking | 3/22 | 11/21 | 2/9* | 1/4 |
Bronchoalveolar Lavage | ||||
Macrophages, % | 48±19 | 84±10 | ||
Lymphocytes, % | 50±19 | 12±7 | ||
Neutrophils , % | 0.8±0.9 | 2.4±3.4 | ||
Eosinophils, % | 1.2±2 | 1.8±2.9 | ||
Pulmonary Function Tests | ||||
DLCO, % predicted | 46±20 | 42±18 | ||
FVC, % predicted | 61±16 | 63±24 | ||
FEV1, % predicted | 64±18 | 68±26 | ||
SpO2, % at rest | 88±4 | 87±5 | ||
SpO2, % during exercise | 75±19 | 81±6 | ||
PaO2 mm Hg** | 54.8±7.2 | 56.2±9 | ||
ePSAP mm Hg | 31±18 | 48±18 |
Mean values are shown ± standard deviation.
* = unknown for 2 controls;
**PaO2 = arterial pressure oxygen; normal values at Mexico City altitude are 67±3 mmHg. SpO2 = pulse oxygen saturation. FEV1 = volume of air expired during the first second. FVC = forced vital capacity. DLCO = carbon dioxide diffusing capacity. ePSAP = estimated systolic pulmonary artery pressure.