Figure 4.

Cytotoxic activity of polyclonal NK cells against tumor cells. (A) CD56⁺/CD3^- effector cells were tested in a ⁵¹Cr release assay, in the presence of antibodies to CD56 (C218) and to NKG2A (Z199) on the indicated targets. (B) Summary of cytotoxicity results (at an E/T ratio of 20:1) with NK cells from 6 donors and 10 tumor cell targets in presence of either C218 (-) or Z199 (+). A line connects statistically significant lytic enhancements by Z199, that is, differences in average values of triplicates more than three times the SD.