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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2011 May 16;35(10):1876–1883. doi: 10.1111/j.1530-0277.2011.01532.x

Figure 4.

Figure 4

Effect of the acute, intraperitoneal administration of the selective AVP V1b receptor antagonist SSR149415 (0, 3, 10, or 30 mg/kg) on alcohol, water, total fluid, and food intake, and preference ratio (defined as the ratio between intake of alcohol solution and total fluid intake) in alcohol-experienced, Sardinian alcohol-preferring (sP) rats exposed to the homecage, 2-bottle “alcohol (10% v/v) vs water” choice regimen with unlimited access for 24 hours/day. Data were collected 6 (panels A–E) and 24 (panels F–L) hours after lights off. SSR149415 was administered 30 min before lights off. Each bar is the mean ± SEM for eight rats. *: p<0.05, **: p<0.01, and ***: p<0.005 with respect to 0 mg/kg SSR149415-treated rat group.