Table 1.
Demographic and main volumetric data of the subjects included in the study
| Patients | Sample 1 | Patients | Sample 2 | |||||
|---|---|---|---|---|---|---|---|---|
| Controls | Statistic | P value | Controls | Statistic | P value | |||
| n | 64 | 56 | 19 | 32 | ||||
| Age (SD) | 33.7 (17.4) | 36.8 (11.9) | t 118 = 1.15 | 0.25 | 32.1 (10.95) | 31.1 (8.26) | t 49 = 0.95 | 0.72 |
| Gender (F:M) | 17:47 | 21:35 | χ2 = 1.65 | 0.20 | 7:12 | 12:20 | χ2 < 0.00 | 0.96 |
| Handedness (R:L:A) | 55:5:3 | 51:4:1 | χ2 = 0.43 | 0.51 | 14:2:3 | 27:4 | χ2 = 1.44 | 0.23 |
| Education (years) | 12.8 (2.5) | 16.27 (2.5) | t 83 = 6.27 | <0.05 | 13 (1.79) | 18.5 (10.5) | t 30 = 1.25 | 0.22 |
| Age at onset | 24.4 (7) | NAa | ||||||
| Duration of illness (years) | 19.1 (16) | NAa | ||||||
| Total volume (cm3) | 1,191,000 (90,000) | 1,220,000 (115,000) | t 120 = 1.44 | 0.15 | 1,204,000 (125,000) | 1,172,000 (106,000) | t 49 = −0.95 | 0.34 |
| Cortical gray matter | 356 (40) | 384 (34) | t 120 = 4.19 | <0.001 | 434 (58) | 432 (38) | t 49 = −0.17 | 0.87 |
| Cortical white matter | 325 (47) | 326 (45) | t 120 = 0.05 | 0.96 | 297 (39) | 290 (36) | t 49 = −0.58 | 0.56 |
| Lateral ventricles | 22 (12) | 19 (8) | t 120 = −1.23 | 0.22 | 23 (17) | 15 (11) | t 23 = −1.35 | 0.19 |
aNot determined in this sample