Table 1.

Genetic risk factors in the development of allergic bronchopulmonary aspergillosis.

(i) HLA-DR restriction and HLA-DQ protection

(a) HLA-DR2 restriction

HLA-DRB1*1501 and *HLA-DRB1*1503

(b) HLA-DR5

HLA-DRB1*1104

(c) HLA-DQ2 protective, decreased in ABPA

DQB1*0201

(ii) IL-4RA polymorphisms

(a) IL-4RA ile75val

(iii) IL-10 polymorphisms

(a) Promoter −1082 GG genotype

(iv) Surfactant protein A2 (SP-A2) polymorphisms

(a) SP-A2 ala91pro

(v) Cystic fibrosis transmembrane conductance regulator (CFTR) mutations

(a) Heterozygous CFTR mutations in asthmatic patients with ABPA

(vi) Toll-like receptor (TLR) polymorphisms

(a) TLR9 T-1237C polymorphism