Table 1.
Entry | 1 | R | Yield (%) | 2 | Yield (%) | |
Meth. Aa | Meth. Bb | |||||
1 | 1a [26] | CH3 | 92 | 2a | 78 | 91 |
2 | 1b [26] | CH2Cl | 82 | 2b | 75 | 90 |
3 | 1c [26] | CH2OC6H5 | 86 | 2c | 76 | 93 |
4 | 1d | CH2O-(p-Cl-C6H4) | 88 | 2d | 72 | 82 |
5 | 1e | CH2O-(o-NO2-C6H4) | 84 | 2e | 75 | 87 |
6 | 1f | CH2O-(p-NO2-C6H4) | 83 | 2f | 74 | 84 |
aMethod A: Swern oxidation; bMethod B: DMP oxidation.