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. 2011 Oct;138(4):381–391. doi: 10.1085/jgp.201110660

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© 2011 Tiffert and Lew

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 4. — Time course of Ca²⁺-induced nucleotide concentration changes in RBCs suspended in substrate-free media. Results are representative of three identical experiments with RBCs from two donors containing slightly different initial ATP concentrations (donor 1, 2.01 and 2.11 mmol/Lcw; donor 2, 1.73 mmol/Lcw). The decline in the total nucleotide concentration is attributed to the breakdown of IMP to hypoxanthine at a rate of ∼0.2 mmol/Lch in the present experimental conditions.