Table III.
Models for Biomarker Prediction of Advanced Coronary Artery Calcium (108 of 3046)
| Model Structure | OR (95% CI) per 1 SD | C-statistic | AIC | p-value§ | |
|---|---|---|---|---|---|
| Base model | 0.808 | 801.91 | |||
| Model 1 | C-reactive protein | 1.15 (0.99, 1.34) | 0.822 | 791.43 | <0.01 |
| D-dimer | 1.13 (1.00, 1.26) | ||||
| Carotid intima media thickness | 1.35 (1.12, 1.62) | ||||
| Model 2 | Low density lipoprotein particle number | 1.28 (0.91, 1.79) | 0.820 | 800.13 | 0.04 |
| C-reactive protein | 1.12 (0.96, 1.31) | ||||
| D-dimer | 1.12 (1.00, 1.26) | ||||
| Cystatin C | 0.90 (0.73, 1.12) | ||||
| Soluble intercellular adhesion molecule-1 | 1.15 (0.88, 1.50) | ||||
| Backward stepwise selection model | D-dimer | 1.13 (1.00, 1.26) | 0.820 | 788.39 | |
| C-reactive protein | 1.16 (1.00, 1.35) | ||||
| Carotid intima media thickness | 1.37 (1.15, 1.65) | ||||
| Age | 1.12 (1.09, 1.15) | ||||
| Gender | 6.44 (3.70, 11.23) | ||||
| Race | 0.71 (0.59, 0.83) | ||||
| Total cholesterol | 1.01 (1.00, 1.02) | ||||
| Current smoking | 2.42 (1.28, 4.60) | ||||
| Hypertension treatment | 2.00 (1.26, 3.19) | ||||