TABLE 2. Cox multivariable analysis of risk factors for graft loss.
| Variablea | Hazard ratio | 95% CI | P |
|---|---|---|---|
| Payback vs. local >0MM | 0.888 | 0.64–1.24 | 0.48 |
| Shipped 0MM vs. local >0MM | 0.718 | 0.55–0.95 | 0.019 |
| DCD vs. DBD | 0.926 | 0.77–1.10 | 0.45 |
| Donor age (yr) | 1.007 | 0.99–1.03 | 0.52 |
| Recipient age (yr) | 0.951 | 0.92–0.98 | 0.002 |
| Transplant No. | 1.128 | 0.95–1.34 | 0.17 |
| Peak PRA (CDC) | 1.005 | 1.001–1.008 | 0.005 |
| Cold storage time (hr) | 1.008 | 0.99–1.02 | 0.16 |
| Total preservation time(hr) | 0.996 | 0.98–1.009 | 0.53 |
| Nondiabetic vs. diabetes mellitusb | 0.661 | 0.54–0.805 | <0.001 |
| Recipient race: other vs. white | 1.261 | 1.012–1.570 | 0.041 |
| Donor race: other vs. white | 0.841 | 0.590–1.198 | 0.34 |
| Recipient BMI (kg/m2) | 1.012 | 0.997–1.028 | 0.12 |
| ESRD duration (mo) | 0.995 | 0.987–1.003 | 0.21 |
| CNI, cyclosporine vs. none | 0.323 | 0.26–0.402 | <0.001 |
| CNI, tacrolimus vs. none | 0.358 | 0.279–0.459 | <0.001 |
| Transplant year | 1.001 | 0.966–1.039 | 0.92 |
a
“A vs. B” should be interpreted as hazard ratio of A relative to B.
b
Includes both types 1 and 2 diabetes.
CI, confidence interval; 0MM, 0-mismatch; DCD, donation after cardiac death; DBD, donation after brain death; PRA, panel reactive antibodies; CDC, complement-dependent cytotoxicty; BMI, body mass index; CNI, calcineurin inhibitor; ESRD, end-stage renal disease.