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Iota toxin shares the same cellular receptor with CDT. (A) FLAG- and FLAG-LSR–transduced LSRGT cells, respectively, and (B) non- and FLAG-LSR–transduced H1-HeLa cells were incubated without (w/o toxin) or with 20 nM iota toxin (+iota toxin) for 24 h, before visualization of intoxication (cell rounding) by microscopy.
