Figure 5.
Representative double and triple deletions/depletions of TNF activities. A-D. Deletion of TNF-induced secretion and recruitment (A), activation and recruitment (B), activation and secretion (G) and activation, recruitment and secretion. E-H depict analogous combinations of targeted TNF depletions. Structures for multiple replicates of each simulation, and for depletions of each combination at 100 days post-infection, are given in Supplement 3.