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. Author manuscript; available in PMC: 2011 Sep 29.
Published in final edited form as: J Immunol. 2009 Mar 15;182(6):3706–3717. doi: 10.4049/jimmunol.0802297

Figure 7.

Figure 7

Effects of losing TNF-induced apoptosis activity on granuloma structures 200 days post-infection. (A) Two characteristic structures that are attainable under apoptosis depletion with total bacterial numbers held constant after day 100. (B) Deletion of apoptosis and TNF-induced secretion. (C) Deletion of both TNF-induced apoptosis and activation. (D) Deletion of both TNF-induced apoptosis and recruitment. In the latter structures, continued bacterial growth after day 100 was permitted. A full list of apoptosis-related deletions are presented in Supplement 3.