Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Models of the Camui sensor for both individual subunits and an assembled holoenzyme. (A) FRET is expected to occur between the fluorophore pair of an inactive subunit. The conformational shift associated with CaMKII activation (ex. via CaM binding) should largely abolish fluorescence transfer. (B) The geometry of the holoenzyme suggests the possibility that intersubunit FRET may occur between fluorophores from adjacent subunits.
