Table 2. Model species and kinetic parameters used in the first model.

Species	Description	Initial Condition/Range
t	Time	[0, 500] min
OP	Lsr-operon concentration	0 M
R	LsrR concentration	0 M
Ap	Phospholyrated AI-2 within cell	0 M
Aout	AI-2 concentration outside the cell	[1], [40] uM

Summary of the initial concentration of the species in the first model and the complete list of kinetic rates that provided the best fit to the experimental data shown in Figure 2B.