Table 4. Kinetic rates used in the modified model.
Parameters | Description | Best fit value (modified model) |
kop | Lsr-operon/Lsr-regulator synthesis rate | 7 uMol−1 min−1 |
kr: | LsrR synthesis rate | 2 min−1 |
k1: | Repression coefficient (Lsr-operon) | 0.2 uMol |
k2: | Repression coefficient (LsrR) | 0.1 uMol |
k3: | AI-2/LsrR binding rate | 0.05 uMol−1 min−1 |
k4 | Repression coefficient (Lsr-regulator) | 65 uMol |
k5 | REG/AI2 interaction | 0.0001 uMol−1 min−1 |
kf | AI-2 flux for the alternative pathway | 0.01 uMol−1 min−1 |
kimp: | AI-2 import rate by Lsr-operon | 0.01 uMol−1 min−1 |
nOP: | Cooperativity coefficient (operon) | 4 |
nR | Cooperativity coefficient (LsrR) | 4 |
kdeg | Protein decay | 0.02 min−1 |
The list of kinetic rates used in the modified model. Two new parameters (k4 and k5) are introduced in the modified model.