Table 2.
Virion-associated cellular protein kinases and their viral substrates
| Family | Genus | Virus | Viral substrate(s) | Virus-associated cellular kinase (s) |
Possible function(s) | References |
|---|---|---|---|---|---|---|
| Retroviridae | Alpharetrovirus | AMV | (?) | 42-46 kDa and 60-64 kDa kinases | 10 to 25 kDa viral protein | [54,129,130] |
| RSV | (?) | Cellular kinase (?) | (?) | [56] | ||
| Betaretrovirus | MMTV | (?) | Cellular kinase (?) | (?) | [56] | |
| Gammaretrovirus | MSV | (?) | Cellular kinase (?) | (?) | [131-133] | |
| R-MLV | (?) | 42-46 kDa and 60-64 kDa Kinases | (?) | [54,129,130] | ||
| FeLV | (?) | Cellular kinase (?) | (?) | [56] | ||
| Deltaretrovirus | HTLV-1 | MA | ERK2 | Virus assembly & release | [6,8] | |
| Lentivirus | HIV-1 | CA, MA, p6 | ERK2, PKA, DR1/2, 53 kDa (?), | Virus infectivity, uncoating | [3,6,7,14,40] | |
| Rev, Nef, Vif | p56lck, PKC, PRP2, Nm23-H1 | Virus release, replication (?) | [62-64,82,88,85] | |||
| SIV | (?) | ERK2, PKA, PKC | (?) | [5,76] | ||
| FIV | (?) | ERK2 | (?) | [76] |
Giroud et al. Table 2