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. 2011 Sep 29;6(9):e25312. doi: 10.1371/journal.pone.0025312

Table 2. Inhibition constants of ATP for human c-NADP-ME.

c-NADP-ME K i,ATP(NAD) (mM) K i,ATP(NADP) (mM)
WT 23.2±1.4 20.6±3.0
E314A 0.73±0.14 18.1±2.6
E314A/S346K 0.73±0.11 17.4±2.6
E314A/S346K/K347Y/K362Q 3.3±0.3 3.9±0.5