Table 3.

Percent of each SFN metabolite and each ERN metabolite relative to total for each respective ITC in the plasma 12 hrs after consumption of broccoli sprouts or broccoli supplement^a

	Broccoli sprouts		Broccoli supplement		p-valuesb
	A/Ac	A/Gd	A/A	A/G	Genotype	Treatment	Interaction
SFN compoundse	%	%	%	%
SFN	0.30 ± 0.04	0.27 ± 0.06	0.04 ± 0.04	0.05 ± 0.05	0.797	0.0004	0.647
SFN-GSH	2.64 ± 0.08	2.87 ± 0.14	2.43 ± 0.19	2.58 ± 0.11	0.194	0.125	0.815
SFN-CG	82.0 ± 1.02	81.0 ± 1.20	89.0 ± 1.19	88.2 ± 0.90	0.574	<0.0001	0.761
SFN-Cys	3.44 ± 0.12	3.67 ± 0.31	3.06 ± 0.18	3.00 ± 0.18	0.740	0.003	0.336
SFN-NAC	11.6 ± 0.96	12.2 ± 0.94	5.51 ± 0.99	6.17 ± 0.87	0.646	<0.0001	0.944
ERN compounds
ERN-GSH	8.39 ± 0.29	9.98 ± 1.09	7.11 ± 0.95	7.76 ± 1.04	0.271	0.043	0.548
ERN-CG	69.4 ± 1.38	67.6 ± 1.19	72.9 ± 1.78	75.1 ± 1.44	0.916	<0.0001	0.022
ERN-Cys	13.6 ± 0.59	14.6 ± 1.20	12.09 ± 0.42	12.1 ± 1.59	0.686	0.002	0.360
ERN-NAC	8.56 ± 1.15	7.77 ± 0.75	7.92 ± 1.67	5.01 ± 1.13	0.311	0.048	0.189

^aMean ± SEM.

^bRepeated measures 2-way ANOVA

^cPositive GSTP1 genotype (n=7)

^dHeterozygous A³¹³G GSTP1 genotype (n=5)

^eFor both SFN and ERN compounds abbreviations are: GSH=glutathione, CG=cysteine-glycine, Cys=cysteine, NAC=N-acetylcysteine